brain function

Research Papers

A network neuroscience of neurofeedback for clinical translation

Murphy, Andrew C., Bassett, Danielle S. (2017) · Current Opinion in Biomedical Engineering

In the emerging field of network neuroscience, the brain is represented as a network of discrete yet functionally and structurally interconnected areas. Mathematical and computational tools to characterize the organization of this network can provide insights into the principles subserving brain structure and function, and can pinpoint differences between healthy individuals and individuals suffering from psychiatric disease or neurological disorders. The field is now faced with the question of how to devise clinical interventions that target these network alterations. Potential solutions to this question include the combination of emerging theories of network control with cutting-edge interventions such as neurofeedback. Each of these techniques may now be mature enough to combine to obtain a theoretically-motivated framework informing viable neuropsychiatric therapies.

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Functional MRI for neurofeedback: feasibility studyon a hand motor task

Yoo, Seung-Schik, Jolesz, Ferenc A. (2002) · Neuroreport

We present an fMRI-based method that enables subjects to monitor and actively modulate their own brain activity as a form of biofeedback. On a 1.5T clinical MR scanner, functional areas during a simple hand motor task were delineated by detecting signal variations associated with the brain activity. Then, the subject adopted a different strategy to expand the activation in motor and somatosensory areas that were not activated previously. Statistical maps of brain activity were visually presented back to the subject, being updated at the end of each segmented rest-task block in near real-time manner. Our results suggest that the visual feedback of the functional brain activation maps guided subjects to adjust their task performance to achieve the desired modulation of cortical activity. This method may offer a potential utility for fMRI-based neurofeedback

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