limbic system
Research Papers
Toward Personalizing Alzheimer’s Disease Therapy Using an Intelligent Cognitive Control System
Subjective cognitive decline is an early state of Alzheimer’s Disease which affects almost 10 million people every year. It results from negative emotions such as frustration which are more present than healthy adults. For this reason, our work focuses on relaxing subjective cognitive decline patients using virtual reality environments to improve their memory performance. We proposed in our previous work a neurofeedback approach which adapts the virtual environment to each patient according to their emotions using a Neural Agent. We found that the Neural Agent can adapt the environment to each participant but have limitations. This work is a continuation of our approach in which we propose a Limbic Agent able to monitor the interactions between the Neural Agent and patients’ emotional reactions, learn from these interactions, and modify the Neural Agent in order to enhance the adaptation to each patient with an Intelligent Cognitive Control System. Our goal is to create a system able to support the Limbic System which is the main area in charge of controlling emotions and creating memory in the human brain. We used data collected form our previous work to train the Limbic Agent and results showed that the agent is capable of modifying the weight of existing rules, generating new intervention rules, and predicting if they will work or not.
Dissociation and Alterations in Brain Function and Structure: Implications for Borderline Personality Disorder
Dissociation involves disruptions of usually integrated functions of consciousness, perception, memory, identity, and affect (e.g., depersonalization, derealization, numbing, amnesia, and analgesia). While the precise neurobiological underpinnings of dissociation remain elusive, neuroimaging studies in disorders, characterized by high dissociation (e.g., depersonalization/derealization disorder (DDD), dissociative identity disorder (DID), dissociative subtype of posttraumatic stress disorder (D-PTSD)), have provided valuable insight into brain alterations possibly underlying dissociation. Neuroimaging studies in borderline personality disorder (BPD), investigating links between altered brain function/structure and dissociation, are still relatively rare. In this article, we provide an overview of neurobiological models of dissociation, primarily based on research in DDD, DID, and D-PTSD. Based on this background, we review recent neuroimaging studies on associations between dissociation and altered brain function and structure in BPD. These studies are discussed in the context of earlier findings regarding methodological differences and limitations and concerning possible implications for future research and the clinical setting.
View Full Paper →Neurofeedback Training to Enhance Learning and Memory in Patients with Cognitive Impairment
The brain tumours can make cognitive impairment especially when they involve the limbic system, the frontal or temporal lobes. The aim of the present study was to examine neurofeedback training (NFT) to enhance learning and memory in patients with cognitive impairment. Single case pre- and post-intervention study was adopted. The qEEG WISC-IV and CBCL test was compared pre and post NFT. Patient was given 40 sessions of NFT, 45 min / day, 3 days a week. The training incorporated video feedback to increase the frequency of Beta waves (15-18 Hz) and to decrease theta waves (3-7 Hz) in T3 and F3. Also, SMR training was performed in Cz to decrease the seizure attacks. qEEG showed prominent different in the brain activity. Results indicated decrease in theta and increase in Beta waves. The present study puts forward that NFT should be taken into account to plan for rehabilitation of patients with cognitive impairment for enhancement of performance in the school or university.
View Full Paper →Ready to Optimize Your Brain?
Schedule a free consultation to discuss limbic system and how neurofeedback training can help
Or call us directly at 855-88-BRAIN
View Programs & Pricing →